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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2003 4
2004 3
2005 5
2006 3
2007 10
2008 5
2009 8
2010 6
2011 9
2012 10
2013 12
2014 9
2015 7
2016 11
2017 6
2018 8
2019 9
2020 10
2021 12
2022 5
2023 7
2024 3

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150 results

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Page 1
BCL2 and MCL1 inhibitors for hematologic malignancies.
Roberts AW, Wei AH, Huang DCS. Roberts AW, et al. Among authors: huang dcs. Blood. 2021 Sep 30;138(13):1120-1136. doi: 10.1182/blood.2020006785. Blood. 2021. PMID: 34320168 Free article. Review.
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
Souers AJ, Leverson JD, Boghaert ER, Ackler SL, Catron ND, Chen J, Dayton BD, Ding H, Enschede SH, Fairbrother WJ, Huang DC, Hymowitz SG, Jin S, Khaw SL, Kovar PJ, Lam LT, Lee J, Maecker HL, Marsh KC, Mason KD, Mitten MJ, Nimmer PM, Oleksijew A, Park CH, Park CM, Phillips DC, Roberts AW, Sampath D, Seymour JF, Smith ML, Sullivan GM, Tahir SK, Tse C, Wendt MD, Xiao Y, Xue JC, Zhang H, Humerickhouse RA, Rosenberg SH, Elmore SW. Souers AJ, et al. Among authors: huang dc. Nat Med. 2013 Feb;19(2):202-8. doi: 10.1038/nm.3048. Epub 2013 Jan 6. Nat Med. 2013. PMID: 23291630
Mesenchymal stromal cell apoptosis is required for their therapeutic function.
Pang SHM, D'Rozario J, Mendonca S, Bhuvan T, Payne NL, Zheng D, Hisana A, Wallis G, Barugahare A, Powell D, Rautela J, Huntington ND, Dewson G, Huang DCS, Gray DHD, Heng TSP. Pang SHM, et al. Among authors: huang dcs. Nat Commun. 2021 Nov 11;12(1):6495. doi: 10.1038/s41467-021-26834-3. Nat Commun. 2021. PMID: 34764248 Free PMC article.
Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia.
Moujalled DM, Brown FC, Chua CC, Dengler MA, Pomilio G, Anstee NS, Litalien V, Thompson E, Morley T, MacRaild S, Tiong IS, Morris R, Dun K, Zordan A, Shah J, Banquet S, Halilovic E, Morris E, Herold MJ, Lessene G, Adams JM, Huang DCS, Roberts AW, Blombery P, Wei AH. Moujalled DM, et al. Among authors: huang dcs. Blood. 2023 Feb 9;141(6):634-644. doi: 10.1182/blood.2022016090. Blood. 2023. PMID: 36219880 Free PMC article.
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
Kotschy A, Szlavik Z, Murray J, Davidson J, Maragno AL, Le Toumelin-Braizat G, Chanrion M, Kelly GL, Gong JN, Moujalled DM, Bruno A, Csekei M, Paczal A, Szabo ZB, Sipos S, Radics G, Proszenyak A, Balint B, Ondi L, Blasko G, Robertson A, Surgenor A, Dokurno P, Chen I, Matassova N, Smith J, Pedder C, Graham C, Studeny A, Lysiak-Auvity G, Girard AM, Gravé F, Segal D, Riffkin CD, Pomilio G, Galbraith LC, Aubrey BJ, Brennan MS, Herold MJ, Chang C, Guasconi G, Cauquil N, Melchiore F, Guigal-Stephan N, Lockhart B, Colland F, Hickman JA, Roberts AW, Huang DC, Wei AH, Strasser A, Lessene G, Geneste O. Kotschy A, et al. Among authors: huang dc. Nature. 2016 Oct 27;538(7626):477-482. doi: 10.1038/nature19830. Epub 2016 Oct 19. Nature. 2016. PMID: 27760111
Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy.
Thijssen R, Tian L, Anderson MA, Flensburg C, Jarratt A, Garnham AL, Jabbari JS, Peng H, Lew TE, Teh CE, Gouil Q, Georgiou A, Tan T, Djajawi TM, Tam CS, Seymour JF, Blombery P, Gray DHD, Majewski IJ, Ritchie ME, Roberts AW, Huang DCS. Thijssen R, et al. Among authors: huang dcs. Blood. 2022 Nov 17;140(20):2127-2141. doi: 10.1182/blood.2022016040. Blood. 2022. PMID: 35709339 Free PMC article.
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
White MJ, McArthur K, Metcalf D, Lane RM, Cambier JC, Herold MJ, van Delft MF, Bedoui S, Lessene G, Ritchie ME, Huang DC, Kile BT. White MJ, et al. Among authors: huang dc. Cell. 2014 Dec 18;159(7):1549-62. doi: 10.1016/j.cell.2014.11.036. Cell. 2014. PMID: 25525874 Free PMC article.
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells.
Wang Z, Burigotto M, Ghetti S, Vaillant F, Tan T, Capaldo BD, Palmieri M, Hirokawa Y, Tai L, Simpson DS, Chang C, Huang AS, Lieschke E, Diepstraten ST, Kaloni D, Riffkin C, Huang DCS, Li Wai Suen CSN, Garnham AL, Gibbs P, Visvader JE, Sieber OM, Herold MJ, Fava LL, Kelly GL, Strasser A. Wang Z, et al. Among authors: huang dcs. Cancer Discov. 2024 Feb 8;14(2):362-379. doi: 10.1158/2159-8290.CD-23-0402. Cancer Discov. 2024. PMID: 37877779 Free PMC article.
The SMARCA4R1157W mutation facilitates chromatin remodeling and confers PRMT1/SMARCA4 inhibitors sensitivity in colorectal cancer.
Zeng X, Yao B, Liu J, Gong GW, Liu M, Li J, Pan HF, Li Q, Yang D, Lu P, Wu D, Xu P, Chen B, Chen P, Zhang M, Zen K, Jing J, Huang DCS, Chen D, Jiang ZW, Zhao Q. Zeng X, et al. Among authors: huang dcs. NPJ Precis Oncol. 2023 Mar 15;7(1):28. doi: 10.1038/s41698-023-00367-y. NPJ Precis Oncol. 2023. PMID: 36922568 Free PMC article.
150 results